Publications

Publications

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(since 2009):

  • Fichtman, B.†, Zagairy, F.†, Biran, N., Barsheshet, Y., Chervinsky, E., Ben Neriah, Z., Shaag, A., Assa, M., Elpeleg O., Harel, A.* and Spiegel, R.* (2019). Combined loss of LAP1B and LAP1C results in an early onset multisystemic nuclear envelopathy. Nature Communications 10: 605.  

    †equal contribution, *corresponding authors. (open access)

  • Fahrenkrog, B. and  Harel, A. (2018). Perturbations in Traffic: Aberrant Nucleocytoplasmic Transport at the Heart of Neurodegeneration. Cells 7: 232. (PDF)
  • Shemesh, E., Hanf, B., Hagag, S., Attias, S., Shadkchan, Y., Fichtman, B., Harel, A., Kruger, T., Brakhage, A.A., Kniemeyer, O. and Osherov N. (2017). Phenotypic and Proteomic Analysis of the Aspergillus fumigatus ΔPrtT, ΔXprG and ΔXprG/ΔPrtT Protease-Deficient Mutants. Front. Microbiol. 8: 2490. (PDF)
  • Hover, T., Maya, T., Ron, S., Sandovsky, H., Shadkchan, Y., Kijner, N., Mitiagin, Y., Fichtman, B., Harel, A., Shanks, R.M.Q., Bruna, R.E., García-Véscovi, E. and Osherov, N. (2016). Analysis of mechanisms of bacterial (Serratia marcescens) attachment, migration and killing of fungal hyphae. Appl. Environ. Microbiol. 82: 2585-2594. (PDF) See: Journal Cover Image
  • Moreira, T.G., Zhang, L., Shaulov, L., Harel, A., Kuss, S.K., Williams, J., Shelton, J., Somatilaka, B., Seemann, J., Yang, J., Sakthivel, R., Nussenzveig, D.R., Faria, A.M.C. and Fontoura, B.M.A. (2015). Sec13 regulates expression of specific immune factors involved in inflammation in vivo. Sci. Rep. 15: 17655. (PDF)
  • Zagairy, F., Fichtman, B. and Harel, A. (2015). The nuclear pore complex and nuclear transport. In: eLS, Cell Biology. John Wiley & Sons Ltd: Chichester, DOI: 10.1002/9780470015902.a0026034. (PDF)
  • Anderson, F., Savulescu, A.F., Rudolph, K., Schipke, J., Cohen, I., Ibiricu, I., Rotem, A., Grünewald, K., Sodeik, B. and Harel, A. (2014). Targeting of viral capsids to nuclear pores in a cell-free reconstitution system. Traffic 15: 1266-1281. (PDF)   See also: Journal Cover Image 
  • Fichtman, B., Shaulov, L. and Harel, A. (2014). Imaging metazoan nuclear pore complexes by field emission scanning electron microscopy. Methods Cell Biol. 122: 41-58. (PDF)
  • Fichtman, B. and Harel, A. (2014). Stress and Aging at the Nuclear Gateway. Mech. Ageing Dev. 135: 24-32. (PDF)
  • Shaulov, L., Fichtman, B. and Harel, A. (2014). High resolution scanning electron microscopy for the imaging of nuclear pore complexes and Ran-mediated transport. Methods Mol. Biol. 1120: 253-261. (PDF) 
  • Weberruss, M.H., Savulescu, A.F., Jando, J., Bissinger, T., Harel, A., Glickman, M.H. and Enenkel, C. (2013). Blm10 facilitates nuclear import of proteasome core particles. EMBO J. 32: 2697-2707. (PDF) 
  • Shaulov, L. and Harel, A. (2012). Improved visualization of vertebrate nuclear pore complexes by field emission scanning electron microscopy. Structure 20: 407-413. (PDF)
  • Roscioli, E., Di Francesco, L., Bolognesi, A., Orlando, S., Giubettini, M., Harel, A., Schininà, M.E. and Lavia, P. (2012). Importin beta negatively regulates multiple aspects of mitosis including RANGAP1 recruitment to kinetochores. J. Cell Biol. 196: 435-450. (PDF)
  • Sabehi, G., Shaulov, L., Silver, D., Yanai, I., Harel, A. and Lindell, D. (2012). A novel lineage of myoviruses infecting marine cyanobacteria is widespread in the oceans. Proc. Natl. Acad. Sci. USA 109: 2037-2042. (PDF)
  • Shaulov, L., Gruber, R., Cohen, I. and Harel, A. (2011). A dominant negative form of POM121 binds chromatin and disrupts the two separate modes of nuclear pore assembly. J. Cell Sci. 124: 3822-3834. (PDF)
  • Savulescu, A.F., Rotem, A. and Harel, A. (2011). Proteasomes crossing the nuclear border. Nucleus 2: 258-263. (PDF)  See also: Journal Cover Image 
  • Harel, A. and Gruenbaum, Y. (2011). Nuclear pore structure: Warming up the core. Cell 146: 191-193. (PDF)
  • Savulescu, A.F., Shorer, H., Kleifeld, O., Cohen, I., Gruber, R., Glickman, M.H. and Harel, A. (2011). Nuclear import of an intact preassembled proteasome particle. Mol. Biol. Cell 22: 880-891.  (PDF)
  • Fichtman, B., Ramos, C., Rasala, B.A., Harel, A. and Forbes D.J. (2010). Inner/outer nuclear membrane fusion in nuclear pore assembly: Biochemical demonstration and molecular analysis. Mol. Biol. Cell 21: 4197-4211.  (PDF)
  • Ciciarello, M., Roscioli, E., Di Fiore, B., Di Francesco, L., Sobrero, F., Bernard D., Mangiacasale, R., Harel, A., Schinina , M.E. and Lavia, P. (2010). Nuclear reformation after mitosis requires down-regulation of the Ran GTPase effector RanBP1 in mammalian cells. Chromosoma 119: 651-668.  (PDF)
  • Rotem, A., Gruber, R., Shorer, H., Shaulov, L., Klein, E. and Harel, A. (2009). Importin Beta regulates the seeding of chromatin with initiation sites for nuclear pore assembly. Mol. Biol. Cell 20: 4031-4042.  (PDF)
  • Lachish-Zalait, A., Lau, C.K., Fichtman, B., Zimmerman, E., Harel, A., Gaylord, M.R., Forbes D.J. and Elbaum, M. (2009). Transportin mediates nuclear entry of DNA in vertebrate systems. Traffic 10: 1414-1428.  (PDF)