Publications

Publications:

 

  1. Journo G, Ahuja A, Dias-Polak D, Eran Y, Bergman R and Shamay M. Global CpG DNA Methylation Footprint in Kaposi’s Sarcoma. Front. Cell. Infect. Microbiol., 09 July 2021 | https://doi.org/10.3389/fcimb.2021.666143

 

  1. Ahuja A, Journo G, Eitan R, Rubin E, Shamay M: High levels of LINE-1 transposable elements expressed in Kaposi’s sarcoma-associated herpesvirus-related primary effusion lymphoma. 2020 Nov 13. doi: 10.1038/s41388-020-01549-9. 

 

  1. Naipauer J, Salyakina D, Journo G, Rosario S, Williams S, Abba M, Shamay M, Mesri EA: High-throughput sequencing analysis of a “hit and run” cell and animal model of KSHV tumorigenesis PLoS Pathog. 2020 Jun 30;16(6):e1008589. doi: 10.1371/journal.ppat.1008589. (Shamay M is co-corresponding author).

 

  1. Shamay M, Kanakry JA, Low JSW, Horowitz NA, Journo G, Ahuja A, Eran Y, Barzilai E, Dann EJ, Stone J, Woo WL, Hsieh WS, Xian RR, Ambinder RF: CpG methylation in cell-free Epstein-Barr virus DNA in patients with EBV-Hodgkin lymphoma. Blood Adv. 2020 Apr 28;4(8):1624-1627. doi:10.1182/bloodadvances.2020001511.

 

  1. Cohen EM, Avital N, Shamay M, Kobiler O: Abortive herpes simplex virus infection of nonneuronal cells results in quiescent viral genomes that can reactivate. Proc Natl Acad Sci U S A. 2019 Dec 23. pii: 201910537. doi: 10.1073/pnas.1910537117. 

 

  1. Tadmor H, Greenway M, Ahuja A, Orgil O, Liao G, Ambinder RF, Hayward SD, Shamay M: Kaposi’s Sarcoma Associated Herpesvirus LANA Modulates the Stability of the E3 Ubiquitin Ligase RLIM. J Virol. 2019 Dec 4. pii: JVI.01578-19. doi: 10.1128/JVI.01578-19. 

 

  1. Journo G, Tushinsky C, Shterngas A, Avital N, Eran Y, Karpuj MV, Frenkel-Morgenstern M, Shamay M: Modulation of Cellular CpG DNA Methylation by Kaposi’s Sarcoma-Associated Herpesvirus. J Virol. 2018 Jul 31;92(16).

 

  1. Simpson S, Fiches G, Jean MJ, Dieringer M, McGuinness J, John SP, Shamay M, Desai P, Zhu J, Santoso NG: Inhibition of Tip60 Reduces Lytic and Latent Gene Expression of Kaposi’s Sarcoma-Associated Herpes Virus (KSHV) and Proliferation of KSHV-Infected Tumor Cells. Front Microbiol. 2018 Apr 24;9:788.

 

  1. Woodard C*, Shamay M*, Liao G, Ng A, Li R, Wan J, Zhu J, Newman R, Rho HS, Hu J, Qian J, Zhu H and Hayward SD: Phosphorylation of the Chromatin Binding Domain of KSHV LANA.  PLoS Pathog. Volume 8, Issue 10, October 2012 (Shamay M is first co-author).

 

  1. Kapoor A, Cai H, Forman M, He R, Shamay M, Arav-Boger R. Human Cytomegalovirus Inhibition by Cardiac Glycosides – Evidence for Involvement of human Ether-a-go-go (hERG) Gene. Antimicrobial Agents and Chemotherapy. 2012 Sep;56(9):4891-9.

 

  1. Shamay M, Liu J, Li R, Liao G, Shen L, Greenway M, Hu S, Zhu J, Xie Z, Ambinder RF, Qian J, Zhu H and Hayward SD: A Protein Array Screen for KSHV LANA Interactors Links LANA to TIP60, PP2A activity and Telomere Shortening. J Virol. 2012 May;86(9):5179-91.

 

  1. Shamay M, Hand N, M. Lemas V, Koon HB, Krown SE, Wrangle J, Desai P, Ramos JC, Ambinder RF: CpG methylation as a tool to characterize cell-free Kaposi’s sarcoma herpesvirus DNA. J Infect Dis. 2012 Apr;205(7):1095-9.

 

  1. Shirley CM, Chen J, Shamay M, Li H, Zahnow CA, Hayward SD, Ambinder RF: Bortezomib induction of C/EBPb mediates Epstein-Barr virus lytic activation in Burkitt’s lymphoma. BLOOD. 2011 Jun 9;117(23):6297-303.

 

  1. Low JSW, Tao Q, Ng KM, Goh HK, Woo WL, Ambinder RF, Srivastava G, Shamay M, Chan AT, Popescu NC, Hsieh WS: A novel isoform of the 8p22 tumor suppressor gene DLC1 suppresses tumor growth and is frequently silenced in multiple common tumors. Oncogene. 2011 Apr 21;30(16):1923-35.

 

  1. Shamay M, Greenway M, Liao G, Ambinder RF, Hayward SD: De-novo DNA methyltransferase DNMT3b interacts with NEDD8 modified proteins. J Biol Chem. 2010 Nov 19; 285(47):36377-86. (Shamay M is the corresponding author).

 

  1. Liu J, Martin H, Shamay M, Woodard C, Tang QQ, Hayward SD: Kaposi’s sarcoma-associated herpesvirus LANA protein downregulates nuclear glycogen synthase kinase 3 activity and consequently blocks differentiation. J Virol. 2007 May; 81(9):4722-31.

 

  1. Shamay M, Krithivas A, Zhang J, Hayward SD: Recruitment of the de novo DNA methyltransferase Dnmt3a by Kaposi’s sarcoma-associated herpesvirus LANA. Proc Natl Acad Sci U S A. 2006 Sep 26;103(39):14554-9.

 

  1. Wang SE, Wu FY, Chen H, Shamay M, Zheng Q, Hayward GS: Early activation of the Kaposi’s sarcoma-associated herpesvirus RTA, RAP, and MTA promoters by the tetradecanoyl phorbol acetate-induced AP1 pathway. J Virol 2004; 78:4248-4267.

 

  1. Shamay M, Barak O, Shaul Y: HBXAP, a novel PHD-finger protein, possesses transcription repression activity. Genomics 2002; 79:523-529.

 

  1. Shamay M, Barak O, Doitsh G, Ben-Dor I, Shaul Y: Hepatitis B virus pX interacts with HBXAP, a PHD finger protein to coactivate transcription. J Biol Chem 2002; 277:9982-9988.

 

  1. Shamay M, Agami R, Shaul Y: HBV integrants of hepatocellular carcinoma cell lines contain an active enhancer. Oncogene 2001; 20:6811-6819.

 

  1. Haviv I, Shamay M, Doitsh G, Shaul Y: Hepatitis B virus pX targets TFIIB in transcription coactivation. Mol Cell Biol 1998; 18:1562-1569.

 

Patents

Patent JHU reference P11863-03 entitled: METHODS FOR DETECTION AND DIFFERENTIATION OF ORIGIN OF VIRAL DNA

Inventors: Ambinder and Shamay