Publications
Moran Titelbaum, Boris Brant, Daniel Baumel, Alina Burstein-Willensky, Shira Perez, Yiftah Barsheshet, and Orly Avni. Ezh2 harnesses the intranuclear actin cytoskeleton to remodel chromatin in differentiating Th cells. iScience sep 2021.
Dror Avni* and Orly Avni*. Extracellular Vesicles: Schistosomal Long-Range Precise Weapon to Manipulate the Immune Response.Front. Cell. Infect. Microbiol., 18 March 2021. *Corresponding authors.
Meningher Tal, Barsheshet Yiftah, Ofir-Birin Yifat, Gold Daniel, Brant Boris, Dekel Elya, Sidi Yechezkel, Schwartz Eli*, Regev-Rudzki Neta*, Avni Orly*, and Avni Dror *. Schistosomal extracellular vesicle-enclosed miRNAs modulate host T helper (CD4+) cell differentiation. EMBO Rep. 2020 Jan 7;21(1). *Corresponding authors.
Werbner M, Barsheshet Y, Werbner N, Zigdon M, Averbuch I, Ziv O, Brant B, Elliot E, Gelberg S, Titelbaum M, Koren O, Avni O. Social-Stress-Responsive Microbiota Induces Stimulation of Self-Reactive Effector T Helper Cells.mSystems. 2019 May 14;4(4).
Nuriel-Ohayon M, Neuman H, Ziv O, Belogolovski A, Barsheshet Y, Bloch N, Uzan A, Lahav R, Peretz A, Frishman S, Hod M, Hadar E, Louzoun Y, Avni O, Koren O.Progesterone Increases Bifidobacterium Relative Abundance during Late Pregnancy. Cell Rep. 2019 Apr 16;27(3):730-736.
Hadar Neuman, Paul Forsythe, Atara Uzan, Orly Avni*and Omry Koren*. Antibiotics in early life: dysbiosis and the damage done.FEMS Microbiology Reviews. In press. *Corresponding authors.
Avni, O*. and Koren, O*. Molecular (Me)micry?Cell Host Microbe. 23, 576-578. *Corresponding authors.
Tzipora C. Falik-Zaccai*, Yiftah Barsheshet, Hanna Mandel, Meital Segev, Avraham Lorber, Shachaf Gelberg, Limor Kalfon, Shani Ben Haroush, Adel Shalata, Liat Gelernter-Yaniv, Sarah Chaim, Dorith Raviv Shay, Morad Khayat, Michal Werbner, Inbar Levia, Yishay Shovala, Galit Talc, Stavit Shalevd, Eli Reuveni, Emily Avitan-Hershi, Eugene Vlodavsky, Liat.Appl-Sarid, Dorit Goldsher, Reuven Bergman, Zvi Segal, Ora Bitterman-Deutsch, and Orly Avni. Sequence variation in PPP1R13L results in a novelform of cardio-cutaneous syndrome. EMBO Mol Med. 2017 9(3):319-336.*Corresponding authors.
Shamriz O, Mizrahi H, Werbner M, Shoenfled Y, Avni O,* and Koren O*. Microbiota at the crossroads of autoimmunity. Autoimmun Rev 2016; 15(9). *Corresponding authors.
Hod-Dvorai R, Jacob E, Boyko Y, and Avni O. The binding activity of Mel-18 at the Il17a promoter is regulated by the integrated signals of the TCR and polarizing cytokines. Eur. J. Immunol. 2011;41:2424-2435.
Jacob E, Hod-Dvorai R, Ben-Mordechai O.L, Boyko Y, Avni O. Dual function of polycomb group proteins in T helper (CD4+) cells.Journal of Molecular Signaling. 2011; 6:5.
Novak R, Jacob E, Haimovich J, Avni O, Melamed D. The MAPK/ERK and PI3K pathways additively coordinate the transcription of recombination-activating genes in B lineage cells.J. Immunol 2010;185:3239-3247.
Scheinman E, Avni O. Transcriptional regulation of GATA3 in T helper cells by the integrated activities of transcription factors downstream of the interleukin-4 receptor and T cell receptor.J Biol Chem 2009;284:3037-3048.
Jacob E, Hod-Dvorai R, Schif-Zuck S, Avni O. Unconventional association of the polycomb group proteins with cytokine genes in differentiated T helper cells.J Biol Chem. 2008;283:13471-13481.
Lee DU, Avni O, Chen L, Rao A. A distal enhancer in the interferon-gamma (IFN-gamma) locus revealed by genome sequence comparison.J Biol Chem. 2004;279:4802-4810.
Avni O., Lee D, Macian F, Szabo SJ, Glimcher LH, Rao A. T(H) cell differentiation is accompanied by dynamic changes in histone acetylation of cytokine genes. Nat Immunol. 2002;3:643-651.
Rao A,Avni O. Molecular aspects of T-cell differentiation.Br Med Bull. 2000;56:969-984.
Avni O, Rao A. T cell differentiation a mechanistic view.Curr Opin Immunol. 2000;12:654-659.
Agarwal S*, Avni O*, Rao A. Cell-type-restricted binding of the transcription factor NFAT to a distal IL-4 enhancer in vivo.Immunity.2000;12:643-652. *Equal contribution
Avni O, Pur Z, Yefenof E, Baniyash M. Complement receptor 3 of macrophages is associated with galectin-1-like protein.J Immunol. 1998;160:6151-6158.
Messika EJ*, Avni O*, Gallily R, Yefenof E, Baniyash M. Identification and characterization of a novel protein associated with macrophage complement receptor 3.J Immunol. 1995;154:6563-6570.*Equal contribution.
Avni O, Yefenof E, Kotler M. Clonal dominance of RadLV-induced lymphomas.Leuk Res. 1995;19:971-976.
Kotler M, Ruchlemer R, Avni O, Yefenof E. Radiation leukemogenesis: quantitative relationship between pre-leukemic cells in the thymus and lymphoma induction.Int J Cancer. 1994;56:761-765.
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